STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
eif5aTranslation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (132 aa)    
Predicted Functional Partners:
rps12
SSU ribosomal protein S12P (rpsL); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 
 0.990
rpl13
LSU ribosomal protein L13P (rplM); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.989
rps17
SSU ribosomal protein S17P (rpsQ); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.988
rpl21e
LSU ribosomal protein L21E; Similar to GP:1215982 percent identity: 39.73; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
 
 
 0.987
rpl18
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.987
rps3ae
SSU ribosomal protein S3AE; Similar to GP:469248 percent identity: 29.17; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
 0.987
rps2
SSU ribosomal protein S2P; Similar to GP:1707827 percent identity: 54.69; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.987
rps7
SSU ribosomal protein S7P (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
 
 
 0.987
rpl14
LSU ribosomal protein L14P (rplN); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.986
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.986
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.