STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1242Methyl coenzyme M reductase system, component A2 (atwA); Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 60.26; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (539 aa)    
Predicted Functional Partners:
MJ_1243
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.71; identified by sequence similarity; putative; Belongs to the UPF0251 family.
  
    0.995
MJ_1244
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 50.00; identified by sequence similarity; putative; To M.jannaschii MJ1245 and M.thermoautotrophicum MTH1110.
  
    0.977
MJ_1245
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1245; To M.jannaschii MJ1244 and M.thermoautotrophicum MTH1110.
  
    0.971
mcrC
Methyl coenzyme M reductase I, operon protein C (mcrC); Similar to GB:M16893 SP:P07960 PID:150057 percent identity: 82.74; identified by sequence similarity; putative.
   
 
 0.957
MJ_0094
Methyl coenzyme M reductase II, operon protein C (mtrC); Similar to GB:M16893 SP:P07960 PID:150057 percent identity: 31.15; identified by sequence similarity; putative.
   
 
 0.935
MJ_0802
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 32.96; identified by sequence similarity; putative.
   
 
 0.935
MJ_0800
(R)-2-hydroxyglutaryl-CoA dehydratase activator; Similar to SP:P11568 GB:X59645 PID:433932 percent identity: 31.78; identified by sequence similarity; putative.
 
     0.877
mcrA
Methyl coenzyme M reductase I, subunit alpha (mcrA); Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
   
 
 0.875
mcrG
Methyl coenzyme M reductase I, subunit gamma (mcrG); Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
   
   0.861
MJ_1089
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 42.68; identified by sequence similarity; putative.
  
 
 0.820
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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