STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1242Methyl coenzyme M reductase system, component A2 (atwA); Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 60.26; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (539 aa)    
Predicted Functional Partners:
MJ_1243
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.71; identified by sequence similarity; putative; Belongs to the UPF0251 family.
  
    0.998
MJ_1244
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 50.00; identified by sequence similarity; putative; To M.jannaschii MJ1245 and M.thermoautotrophicum MTH1110.
  
    0.970
MJ_1245
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1245; To M.jannaschii MJ1244 and M.thermoautotrophicum MTH1110.
  
    0.967
MJ_1089
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 42.68; identified by sequence similarity; putative.
  
 
 0.892
MJ_1571
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 27.87; identified by sequence similarity; putative.
  
 
 0.892
MJ_1572
Cobalt transport ATP-binding protein (cbiO); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
0.790
ecfA
Cobalt transport ATP-binding protein (cbiO); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
0.788
MJ_0800
(R)-2-hydroxyglutaryl-CoA dehydratase activator; Similar to SP:P11568 GB:X59645 PID:433932 percent identity: 31.78; identified by sequence similarity; putative.
 
     0.778
cfbD
Vanadium nitrogenase-associated protein N; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c- acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.727
hdrB1
Heterodisulfide reductase, subunit B1 (hdrB1); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
  
 0.711
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.