STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1254Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1254. (469 aa)    
Predicted Functional Partners:
secF
Protein translocase, subunit SECF (secF); Involved in protein export.
 
     0.869
MJ_1255
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1255; Belongs to the glycosyltransferase 28 family.
  
    0.790
cofD
Conserved hypothetical protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
  
    0.787
MJ_1257
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1257.
       0.737
MJ_1258
Archaeal histone A3; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (in vitro).
 
     0.626
MJ_0774
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0774.
 
     0.574
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity).
  
    0.515
MJ_1488
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1488.
 
     0.457
MJ_1128
Conserved hypothetical protein; Similar to SP:P46555 percent identity: 32.32; identified by sequence similarity; putative.
  
     0.424
endA
tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
     0.415
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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