STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1266High-affinity branched-chain amino acid transport protein (braC); Similar to GB:D90223 SP:P21175 GB:M31071 PID:151110 PID:216863 percent identity: 24.92; identified by sequence similarity; putative. (417 aa)    
Predicted Functional Partners:
livM
High-affinity branched-chain amino acid transport protein (braE); Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
 
 
 0.999
livG
High-affinity branched-chain amino acid transport ATP-binding protein (braF); Probable component of a branched-chain amino-acid transport system; Belongs to the ABC transporter superfamily.
 
 
 0.998
livH
High-affinity branched-chain amino acid transport protein (braD); Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
 
 
 0.998
livF
High-affinity branched-chain amino acid transport ATP-binding protein (braG); Probable component of a branched-chain amino-acid transport system.
 
 
 0.995
ndk
Nucleoside diphosphate kinase, (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.529
ilvC
Ketol-acid reductoisomerase (ilvC); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.456
tmk
Thymidylate kinase (tmk); Similar to SP:P36590 percent identity: 31.18; identified by sequence similarity; putative.
  
    0.455
guaAB
GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP.
  
    0.455
hemL
Glutamate-1-semialdehyde aminotransferase (hemL); Similar to GB:M57676 SP:P30949 PID:143040 GB:AL009126 percent identity: 51.67; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
  
    0.454
guaAA
GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP.
  
    0.438
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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