STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1275NA(+)/H(+) antiporter (napA); This is probably a Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (388 aa)    
Predicted Functional Partners:
MJ_1485
TRK system potassium uptake protein (trkG); Similar to SP:P23849 GB:X56783 PID:43140 GB:U00096 PID:1742227 percent identity: 28.23; identified by sequence similarity; putative.
  
 
 0.620
dphB
Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
       0.599
trkA
TRK system potassium uptake protein (trkA); Part of a potassium transport system.
  
  
 0.564
MJ_1226
Plasma membrane ATPase 1 (aha1); Similar to SP:P20649 percent identity: 44.42; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
  
 
 0.545
phi
Conserved hypothetical protein; Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate; Belongs to the SIS family. PHI subfamily.
 
     0.501
guaAA
GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP.
 
     0.500
MJ_1187
Dinitrogenase reductase activating glycohydrolase (draG); Similar to SP:P14300 GB:X16187 PID:46391 percent identity: 29.78; identified by sequence similarity; putative; Belongs to the ADP-ribosylglycohydrolase family.
 
  
 0.487
MJ_0664
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0664.
     
 0.453
topA
DNA topoisomerase I (topA) {Bacillus subtilis; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken stra [...]
     
 0.452
MJ_1631
Glycogen phosphorylase (glgP); Similar to GB:Z25795 SP:P39123 PID:397492 PID:2293140 GB:AL009126 percent identity: 27.95; identified by sequence similarity; putative; Belongs to the glycogen phosphorylase family.
     
 0.435
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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