STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1313Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 55.44; identified by sequence similarity; putative; To M.thermoautotrophicum MTH1421. (403 aa)    
Predicted Functional Partners:
MJ_1407
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 48.00; identified by sequence similarity; putative; Belongs to the UPF0107 family.
 
 
 0.996
cobD
Cobalamin biosynthesis protein B (cbiB); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.952
MJ_1315
Conserved hypothetical protein; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA (By similarity).
       0.927
MJ_1312
Conserved hypothetical protein; Similar to GP:1653753 percent identity: 33.00; identified by sequence similarity; putative.
       0.837
MJ_1316
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.46; identified by sequence similarity; putative; Belongs to the UPF0248 family.
       0.778
MJ_1130
O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...]
       0.748
MJ_1133
Conserved hypothetical protein; Similar to SP:P22349 GB:X02586 PID:44543 percent identity: 45.85; identified by sequence similarity; putative; Belongs to the UbiD family.
 
     0.573
MJ_1311
Conserved hypothetical protein; Similar to SP:P42419 PID:709989 GB:AL009126 percent identity: 31.82; identified by sequence similarity; putative; To M.jannaschii MJ1614 and MJ0008.
       0.492
ubiX
Phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
       0.431
MJ_0971
Conserved hypothetical protein; Similar to GP:1707806 percent identity: 29.74; identified by sequence similarity; putative.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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