| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_1130 | MJ_1332 | MJ_1130 | MJ_1332 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.866 |
| MJ_1130 | argS | MJ_1130 | MJ_0237 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | arginyl-tRNA synthetase (argS); Identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.799 |
| MJ_1130 | rpl11 | MJ_1130 | MJ_0373 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L11P (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.664 |
| MJ_1130 | rpl13 | MJ_1130 | MJ_0194 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L13P (rplM); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.642 |
| MJ_1130 | rpl14 | MJ_1130 | MJ_0466 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L14P (rplN); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.698 |
| MJ_1130 | rpl15 | MJ_1130 | MJ_0477 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L15P (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.438 |
| MJ_1130 | rpl2 | MJ_1130 | MJ_0179 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L2P (rplB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.561 |
| MJ_1130 | rpl3 | MJ_1130 | MJ_0176 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L3P (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.504 |
| MJ_1130 | rpl5 | MJ_1130 | MJ_0469 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L5P (rplE); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.599 |
| MJ_1130 | rpl6 | MJ_1130 | MJ_0471 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | LSU ribosomal protein L6P (rplF); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.437 |
| MJ_1332 | MJ_1130 | MJ_1332 | MJ_1130 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | 0.866 |
| MJ_1332 | argS | MJ_1332 | MJ_0237 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | arginyl-tRNA synthetase (argS); Identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.867 |
| MJ_1332 | rpl11 | MJ_1332 | MJ_0373 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L11P (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.866 |
| MJ_1332 | rpl13 | MJ_1332 | MJ_0194 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L13P (rplM); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.886 |
| MJ_1332 | rpl14 | MJ_1332 | MJ_0466 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L14P (rplN); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.873 |
| MJ_1332 | rpl15 | MJ_1332 | MJ_0477 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L15P (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.845 |
| MJ_1332 | rpl2 | MJ_1332 | MJ_0179 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L2P (rplB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.892 |
| MJ_1332 | rpl3 | MJ_1332 | MJ_0176 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L3P (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.862 |
| MJ_1332 | rpl5 | MJ_1332 | MJ_0469 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L5P (rplE); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.893 |
| MJ_1332 | rpl6 | MJ_1332 | MJ_0471 | GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L6P (rplF); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.854 |
