Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1334UDP-glucose pyrophosphorylase (gtaB); Similar to GB:U02258 GB:L43967 SP:P47691 PID:406922 PID:1046172 percent identity: 46.21; identified by sequence similarity; putative. (283 aa)    
Predicted Functional Partners:
MJ_1054
UDP-glucose dehydrogenase, putative; Similar to GP:1651923 percent identity: 43.32; identified by sequence similarity; putative.
  
 0.990
MJ_0211
UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity). Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.963
glmU
Glucose-1-phosphate thymidylyltransferase (strD); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP-GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1-P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate. Also catalyzes the reverse reaction, i.e. the cleavage of UDP-GlcNAc with pyrophosphate to form UTP and GlcNAc-1-P. To a lesser extent, is also able to use dUTP or dTTP as the nucleotide substrate, but not CTP, ATP or GTP; In the N-terminal section; belongs to the N- [...]
 
  
0.938
MJ_1631
Glycogen phosphorylase (glgP); Similar to GB:Z25795 SP:P39123 PID:397492 PID:2293140 GB:AL009126 percent identity: 27.95; identified by sequence similarity; putative; Belongs to the glycogen phosphorylase family.
    
 0.919
wecB
Lipopolysaccharide biosynthesis protein (wbpI); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP- ManNAc), the activated donor of ManNAc residues; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 
 0.906
MJ_1055
Capsular polysaccharide biosynthesis protein I; Similar to GB:U10927 SP:P39858 PID:506705 percent identity: 50.32; identified by sequence similarity; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
 
 0.879
manB
Phosphomannomutase (pmmA); Catalyzes the formation of mannose-1-P from mannose-6-P. Can also use glucose-1-P.
   
 0.788
MJ_1333.1
Hypothetical protein; Brute Force ORF; identified by GeneMark; putative; M. jannaschii predicted coding region MJ1333.1.
       0.722
MJ_0092
Heterodisulfide reductase, subunit D (hdrD); Similar to GP:1890198 percent identity: 31.87; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
       0.698
pgi
Glucose-6-phosphate isomerase; Catalyzes the isomerization of glucose-6-P to fructose-6-P.
 
 
 
 0.678
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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