STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1339Protein with ATP/GTP-binding site; Similar to SP:P04766 GB:X04399 PID:39954 percent identity: 32.65; identified by sequence similarity; putative; To M.thermoautotrophicum MTH765. (154 aa)    
Predicted Functional Partners:
ftsY
Signal recognition particle, receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
   
 0.988
MJ_1340
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.40; identified by sequence similarity; putative; To M.jannaschii MJ0310 and MJ0714.
  
 
 0.987
MJ_1338
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase related protein; Similar to SP:P32440 GB:U19363 GB:U19364 GB:X59547 PID:48909 percent identity: 29.09; identified by sequence similarity; putative; Belongs to the HMD family.
  
    0.984
MJ_0310
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 60.53; identified by sequence similarity; putative.
  
 
 0.972
MJ_0714
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.40; identified by sequence similarity; putative; To M.jannaschii MJ0310 and MJ1340.
  
 
 0.972
MJ_0715
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase-related protein (hmd); Similar to PID:1149527 SP:Q50840 percent identity: 29.86; identified by sequence similarity; putative; Belongs to the HMD family.
  
    0.954
MJ_0311
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0311.
  
 
 0.937
MJ_1389
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1389.
  
 
 0.937
srp54
Signal recognition particle, subunit SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
 
 0.892
srp19
Signal recognition particle, subunit SRP19; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
   
 
 0.872
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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