Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
truD2Conserved hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (487 aa)    
Predicted Functional Partners:
MJ_1365
Pheromone shutdown protein (traB); Similar to GB:U00681 PID:388268 PID:475428 percent identity: 30.39; identified by sequence similarity; putative.
 
     0.877
MJ_1464
Hypothetical GTP-binding protein (SP:P40010); Similar to SP:P40010 PID:603598 percent identity: 34.59; identified by sequence similarity; putative; Belongs to the TRAFAC class YlqF/YawG GTPase family.
  
 
 0.790
rpl3
LSU ribosomal protein L3P (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
   0.764
rpl24
LSU ribosomal protein L24P (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
   0.737
engB
Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
   
   0.718
rpl15
LSU ribosomal protein L15P (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
   0.717
rps5
SSU ribosomal protein S5P (rpsE); With S4 and S12 plays an important role in translational accuracy.
  
   0.715
rpl13
LSU ribosomal protein L13P (rplM); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.713
rpl11
LSU ribosomal protein L11P (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
   
   0.711
rps2
SSU ribosomal protein S2P; Similar to GP:1707827 percent identity: 54.69; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
  
   0.703
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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