Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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uppSConserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (280 aa)    
Predicted Functional Partners:
idsA
Bifunctional short chain isoprenyl diphosphate synthase (idsA); Similar to PID:913252 SP:Q53479 percent identity: 48.47; identified by sequence similarity; putative.
 
 
 0.988
MJ_1371
Methlytransferase; Similar to GP:2437836 percent identity: 39.09; identified by sequence similarity; putative; Belongs to the MtxX family.
  
    0.943
MJ_1373
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1373.
       0.938
MJ_1370
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1370; Belongs to the UPF0285 family.
       0.931
nusA
Putative transcription termination-antitermination factor (NusA); Participates in transcription termination. Belongs to the NusA family.
  
    0.828
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.816
MJ_0971
Conserved hypothetical protein; Similar to GP:1707806 percent identity: 29.74; identified by sequence similarity; putative.
  
  
 0.787
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.779
MJ_1113
N-acetylglucosamine-1-phosphate transferase; Similar to GB:D28748 SP:P39465 PID:506372 percent identity: 28.00; identified by sequence similarity; putative.
 
  
 0.736
trm14
Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA(Cys).
  
    0.729
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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