| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_0541 | MJ_1385 | MJ_0541 | MJ_1385 | Conserved hypothetical protein; Similar to GP:1001812 percent identity: 32.62; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.842 |
| MJ_0541 | nac | MJ_0541 | MJ_0280 | Conserved hypothetical protein; Similar to GP:1001812 percent identity: 32.62; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.451 |
| MJ_0667 | MJ_1385 | MJ_0667 | MJ_1385 | Thymidine phosphorylase (deoA); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.685 |
| MJ_0778 | MJ_1385 | MJ_0778 | MJ_1385 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 53.85; identified by sequence similarity; putative. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.973 |
| MJ_0778 | tfe | MJ_0778 | MJ_0777 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 53.85; identified by sequence similarity; putative. | Putative transcription initiation factor (TFIIE, subunit alpha); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.927 |
| MJ_1383 | MJ_1384 | MJ_1383 | MJ_1384 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 42.44; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. | NADH oxidase; Similar to GB:AE000782 percent identity: 43.64; identified by sequence similarity; putative. | 0.861 |
| MJ_1383 | MJ_1385 | MJ_1383 | MJ_1385 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 42.44; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.836 |
| MJ_1384 | MJ_1383 | MJ_1384 | MJ_1383 | NADH oxidase; Similar to GB:AE000782 percent identity: 43.64; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 42.44; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. | 0.861 |
| MJ_1384 | MJ_1385 | MJ_1384 | MJ_1385 | NADH oxidase; Similar to GB:AE000782 percent identity: 43.64; identified by sequence similarity; putative. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.761 |
| MJ_1385 | MJ_0541 | MJ_1385 | MJ_0541 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Similar to GP:1001812 percent identity: 32.62; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | 0.842 |
| MJ_1385 | MJ_0667 | MJ_1385 | MJ_0667 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Thymidine phosphorylase (deoA); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | 0.685 |
| MJ_1385 | MJ_0778 | MJ_1385 | MJ_0778 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 53.85; identified by sequence similarity; putative. | 0.973 |
| MJ_1385 | MJ_1383 | MJ_1385 | MJ_1383 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 42.44; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. | 0.836 |
| MJ_1385 | MJ_1384 | MJ_1385 | MJ_1384 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | NADH oxidase; Similar to GB:AE000782 percent identity: 43.64; identified by sequence similarity; putative. | 0.761 |
| MJ_1385 | MJ_1387 | MJ_1385 | MJ_1387 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Similar to PID:1651806 percent identity: 33.88; identified by sequence similarity; putative; Belongs to the LarC family. | 0.698 |
| MJ_1385 | aglB | MJ_1385 | MJ_1525 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative transmembrane oligosaccharyl transferase; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcGlc-2,3-diNAcAGlcNAc in Methanococci) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. Involved in the assembly of an N-linked disaccharide that decorates the S-layer glycoprotein and flagellins. | 0.689 |
| MJ_1385 | nac | MJ_1385 | MJ_0280 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.765 |
| MJ_1385 | tfe | MJ_1385 | MJ_0777 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative transcription initiation factor (TFIIE, subunit alpha); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.790 |
| MJ_1385 | tgtA | MJ_1385 | MJ_0436 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Queuine tRNA-ribosyltransferase (tgtA); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. Can also utilize guanine as substrate. | 0.836 |
| MJ_1387 | MJ_1385 | MJ_1387 | MJ_1385 | Conserved hypothetical protein; Similar to PID:1651806 percent identity: 33.88; identified by sequence similarity; putative; Belongs to the LarC family. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.698 |