STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1399Alignment in; Identified by sequence similarity; putative; Belongs to the UPF0200 family. (197 aa)    
Predicted Functional Partners:
MJ_1400
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1400.
  
    0.940
MJ_0209
Conserved hypothetical protein; Catalyzes the condensation of (R)-4-phosphopantoate and beta- alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway. Belongs to the archaeal phosphopantothenate synthetase family.
 
     0.766
pyrB
Aspartate carbamoyltransferase catalytic chain (pyrB); Similar to GP:1572497 percent identity: 59.12; identified by sequence similarity; putative.
 
  
 0.764
MJ_1564
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1564; Belongs to the UPF0201 family.
 
    0.763
MJ_0003
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0003.
 
     0.720
cca
tRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
 
     0.710
MJ_1401
Putative ATP dependent RNA helicase; Similar to SP:P32639 PID:603413 percent identity: 29.62; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
 
     0.686
MJ_1227
Pyruvate formate-lyase activating enzyme (act); Similar to GB:L42023 SP:P43751 PID:1003258 PID:1222095 PID:1204435 percent identity: 35.58; identified by sequence similarity; putative.
       0.666
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.594
nth
Endonuclease III (nth1); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 0.588
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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