Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrIAspartate carbamoyltransferase regulatory chain (pyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (149 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase catalytic chain (pyrB); Similar to GP:1572497 percent identity: 59.12; identified by sequence similarity; putative.
 0.999
carA
Carbamoyl-phosphate synthase, small (or glutamine) subunit (carA); Similar to GB:M59757 SP:P25993 PID:143389 GB:AL009126 percent identity: 48.55; identified by sequence similarity; putative; Belongs to the CarA family.
  
 
 0.966
carB1
Carbamoyl-phosphate synthase, medium subunit (carB1); Similar to GB:D10483 SP:P00968 GB:J01597 GB:V01500 PID:145464 percent identity: 53.32; identified by sequence similarity; putative; Belongs to the CarB family.
  
 
 0.961
carB2
Carbamoyl-phosphate synthase, large subunit (carB2); Similar to GB:D10483 SP:P00968 GB:J01597 GB:V01500 PID:145464 percent identity: 52.95; identified by sequence similarity; putative; Belongs to the CarB family.
  
 
 0.961
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
    
 0.960
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.946
pyrF
Conserved hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.927
MJ_0001
Aspartate aminotransferase (aspB1); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 44.38; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
    
  0.902
argG
Argininosuccinate synthetase (argG); Similar to GB:M21315 SP:P13256 PID:150046 percent identity: 71.90; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
    
  0.902
MJ_1056
Asparagine synthetase (asnB); Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277 percent identity: 32.95; identified by sequence similarity; putative; Belongs to the asparagine synthetase family.
    
  0.902
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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