STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1437L-2-haloalkanoic acid dehalogenase isolog; Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro; Belongs to the HAD-like hydrolase superfamily. (228 aa)    
Predicted Functional Partners:
MJ_1436
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 59.21; identified by sequence similarity; putative; To M.thermoautotrophicum MTH1236.
       0.927
cobS
Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
       0.779
MJ_1439
Thermonuclease; Similar to GB:L23973 SP:P43270 PID:532653 percent identity: 36.72; identified by sequence similarity; putative; Belongs to the thermonuclease family.
     
 0.756
MJ_1065
Spore coat polysaccharide biosynthesis protein E; Similar to GB:X73124 SP:P39625 PID:413991 GB:AL009126 percent identity: 37.83; identified by sequence similarity; putative; To B.subtilis SpsE.
  
  
 0.576
guaB
Inosine-5'-monophosphate dehydrogenase, (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.534
aroK
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 44.16; identified by sequence similarity; putative.
       0.520
MJ_1435
Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ1435.
       0.495
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.489
dapF
Diaminopimelate epimerase (dapF); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
     
 0.467
argB
Acetylglutamate kinase (argB); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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