STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1439Thermonuclease; Similar to GB:L23973 SP:P43270 PID:532653 percent identity: 36.72; identified by sequence similarity; putative; Belongs to the thermonuclease family. (207 aa)    
Predicted Functional Partners:
aroK
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 44.16; identified by sequence similarity; putative.
       0.892
cobS
Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
       0.780
MJ_1437
L-2-haloalkanoic acid dehalogenase isolog; Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro; Belongs to the HAD-like hydrolase superfamily.
     
 0.756
MJ_1436
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 59.21; identified by sequence similarity; putative; To M.thermoautotrophicum MTH1236.
       0.747
hmvA
DNA binding protein; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (in vitro).
     
 0.666
MJ_1375
SpoVB isolog; Similar to GB:D26185 SP:P37555 PID:467446 GB:AL009126 percent identity: 23.61; identified by sequence similarity; putative.
  
  
 0.534
MJ_1435
Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ1435.
     
 0.487
MJ_1080
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1080.
   
    0.463
MJ_0669
ATP-dependent RNA helicase, DEAD-family (deaD); Similar to GB:L42023 SP:P44586 PID:1003361 PID:1222156 PID:1204489 percent identity: 43.17; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
   
 0.447
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
   
 0.447
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: high (88%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.