STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1458Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 58.60; identified by sequence similarity; putative. (218 aa)    
Predicted Functional Partners:
htpX
Heat shock protein HtpX, possibly protease (htpX); Similar to GB:M58470 SP:P23894 PID:146412 GB:U00096 PID:1736470 percent identity: 34.96; identified by sequence similarity; putative; Belongs to the peptidase M48B family.
  
    0.987
hemD
Uroporphyrinogen III synthase (hemD); Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.899
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala) (By similarity). Also functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala), and maybe also from Gly-tRNA(Ala).
  
    0.768
ade
Adenine deaminase (adeC); Similar to GB:D37799 SP:P39761 GB:X83795 PID:633167 PID:1065989 percent identity: 35.99; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.751
hisD
Histidinol dehydrogenase (hisD); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.616
MJ_1457
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1457.
       0.599
MJ_0959
Aspartate aminotransferase (aspC); Similar to PID:704449 GB:AE000666 percent identity: 54.69; identified by sequence similarity; putative.
  
    0.535
MJ_0969
Conserved hypothetical protein; Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.
  
    0.507
purD
Phosphoribosylamine--glycine ligase (purD); Similar to GB:J02732 SP:P12039 PID:143374 GB:AL009126 percent identity: 33.73; identified by sequence similarity; putative.
  
    0.479
trpS
tryptophanyl-tRNA synthetase (trpS); Similar to GB:X59892 GB:X67918 GB:X67919 GB:X67920 GB:X67921 percent identity: 31.02; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
    0.463
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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