Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_0099 | MJ_0100 | MJ_0099 | MJ_0100 | Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative. | 0.999 |
| MJ_0099 | MJ_1388 | MJ_0099 | MJ_1388 | Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative. | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | 0.900 |
| MJ_0099 | hom | MJ_0099 | MJ_1602 | Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative. | Homoserine dehydrogenase (hom); Similar to SP:P19582 GB:M23217 PID:558494 PID:809663 GB:AL009126 percent identity: 40.32; identified by sequence similarity; putative; Belongs to the homoserine dehydrogenase family. | 0.900 |
| MJ_0099 | metE | MJ_0099 | MJ_1473 | Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity). | 0.900 |
| MJ_0100 | MJ_0099 | MJ_0100 | MJ_0099 | Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative. | Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative. | 0.999 |
| MJ_0100 | MJ_1388 | MJ_0100 | MJ_1388 | Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative. | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | 0.900 |
| MJ_0100 | hom | MJ_0100 | MJ_1602 | Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative. | Homoserine dehydrogenase (hom); Similar to SP:P19582 GB:M23217 PID:558494 PID:809663 GB:AL009126 percent identity: 40.32; identified by sequence similarity; putative; Belongs to the homoserine dehydrogenase family. | 0.903 |
| MJ_0100 | metE | MJ_0100 | MJ_1473 | Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity). | 0.901 |
| MJ_0969 | ilvC | MJ_0969 | MJ_1543 | Conserved hypothetical protein; Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway. | Ketol-acid reductoisomerase (ilvC); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.771 |
| MJ_0969 | metE | MJ_0969 | MJ_1473 | Conserved hypothetical protein; Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity). | 0.825 |
| MJ_1388 | MJ_0099 | MJ_1388 | MJ_0099 | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative. | 0.900 |
| MJ_1388 | MJ_0100 | MJ_1388 | MJ_0100 | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative. | 0.900 |
| MJ_1388 | glyA | MJ_1388 | MJ_1597 | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. The use of tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate is 450-fold less efficient than that of H4MPT. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo- beta-phenylserine; Belongs to the SHMT family. | 0.751 |
| MJ_1388 | hom | MJ_1388 | MJ_1602 | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | Homoserine dehydrogenase (hom); Similar to SP:P19582 GB:M23217 PID:558494 PID:809663 GB:AL009126 percent identity: 40.32; identified by sequence similarity; putative; Belongs to the homoserine dehydrogenase family. | 0.845 |
| MJ_1388 | metE | MJ_1388 | MJ_1473 | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity). | 0.988 |
| MJ_1388 | thrB | MJ_1388 | MJ_1104 | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | Homoserine kinase (thrB); Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.809 |
| glyA | MJ_1388 | MJ_1597 | MJ_1388 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. The use of tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate is 450-fold less efficient than that of H4MPT. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo- beta-phenylserine; Belongs to the SHMT family. | Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family. | 0.751 |
| glyA | hom | MJ_1597 | MJ_1602 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. The use of tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate is 450-fold less efficient than that of H4MPT. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo- beta-phenylserine; Belongs to the SHMT family. | Homoserine dehydrogenase (hom); Similar to SP:P19582 GB:M23217 PID:558494 PID:809663 GB:AL009126 percent identity: 40.32; identified by sequence similarity; putative; Belongs to the homoserine dehydrogenase family. | 0.856 |
| glyA | ilvC | MJ_1597 | MJ_1543 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. The use of tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate is 450-fold less efficient than that of H4MPT. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo- beta-phenylserine; Belongs to the SHMT family. | Ketol-acid reductoisomerase (ilvC); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.553 |
| glyA | metE | MJ_1597 | MJ_1473 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. The use of tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate is 450-fold less efficient than that of H4MPT. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo- beta-phenylserine; Belongs to the SHMT family. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity). | 0.721 |
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