STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1475Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1475. (125 aa)    
Predicted Functional Partners:
nob1
Ribosomal protein S15A isolog; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family.
       0.873
trmJ
Conserved hypothetical protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) at position 32 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.778
MJ_1477
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1477.
       0.777
trm5b
Conserved hypothetical protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs.
       0.482
top6A
DNA topoisomerase VI, subunit A (top6A); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.431
MJ_0443
Conserved hypothetical protein; Similar to GB:X59720 SP:P25586 PID:5300 percent identity: 27.78; identified by sequence similarity; putative.
       0.431
rio1
Conserved hypothetical protein; Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity).
       0.431
eIF1A
Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
       0.431
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. It is also able to utilize a variety of GTP analogs as substrates, including GDP, beta,gamma-methylene-GTP and GTP-[gamma- thio]; Belongs to the GTP cyclohydrolase IV family.
       0.431
top6B
DNA topoisomerase VI, subunit B (top6B); Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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