Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1496Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 35.35; identified by sequence similarity; putative; Belongs to the UPF0127 family. (117 aa)    
Predicted Functional Partners:
MJ_1495
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 58.61; identified by sequence similarity; putative.
       0.956
MJ_1497
Acetylornithine deacetylase (argE); Similar to SP:P23908 GB:X55417 GB:X62807 PID:396304 PID:40955 percent identity: 26.01; identified by sequence similarity; putative.
       0.932
MJ_1494
AAA superfamily ATPase, similar to FtsH; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
       0.847
mjaVM
Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence GTAC, causes specific methylation on C-4 on both strands, and protects the DNA from cleavage by the MjaV endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
       0.745
purL
Phosphoribosylformylglycinamidine synthase II (purL); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
       0.423
MJ_0463
Conserved hypothetical protein; Similar to SP:P14021 PID:44755 percent identity: 78.43; identified by sequence similarity; putative; Belongs to the SUI1 family.
       0.417
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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