Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MJ_1508ABC transporter, probable ATP-binding subunit; Similar to GB:L42023 SP:P45247 PID:1007753 PID:1221696 PID:1205784 percent identity: 43.89; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (224 aa)    
Predicted Functional Partners:
MJ_1507
Hypothetical protein; Similar to PID:1653948 percent identity: 32.05; identified by sequence similarity; putative.
 
 0.999
MJ_0797
Hypothetical protein; Similar to PID:1653948 percent identity: 28.10; identified by sequence similarity; putative.
 
 0.992
MJ_0687
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 40.25; identified by sequence similarity; putative.
   
 
 0.720
MJ_1506
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1506.
  
    0.654
rpl2
LSU ribosomal protein L2P (rplB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
     0.554
argS
arginyl-tRNA synthetase (argS); Identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
     0.537
MJ_1509
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1509.
       0.503
selB
Putative translation factor, EF-1 alpha family; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. SelB subfamily.
 
     0.472
rpl14
LSU ribosomal protein L14P (rplN); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
     0.432
MJ_1023
ABC transporter ATP-binding protein; Similar to SP:P26946 GB:X59424 PID:39478 percent identity: 49.17; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
0.418
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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