| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_0104 | taw3 | MJ_0104 | MJ_1510 | DNA-binding protein, probably DNA helicase; Similar to GB:M64979 GB:L14754 GB:L24544 SP:P38935 PID:401776 percent identity: 34.98; identified by sequence similarity; putative; Belongs to the DNA2/NAM7 helicase family. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.729 |
| MJ_1511 | rgy | MJ_1511 | MJ_1512 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.43; identified by sequence similarity; putative. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.454 |
| MJ_1511 | taw3 | MJ_1511 | MJ_1510 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.43; identified by sequence similarity; putative. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.514 |
| MJ_1559 | rgy | MJ_1559 | MJ_1512 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.481 |
| MJ_1559 | taw3 | MJ_1559 | MJ_1510 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.505 |
| endA | taw2 | MJ_1424 | MJ_1557 | tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | Met-10+ related protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). | 0.503 |
| endA | taw3 | MJ_1424 | MJ_1510 | tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.526 |
| endA | trm5b | MJ_1424 | MJ_0883 | tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | Conserved hypothetical protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs. | 0.425 |
| pstK | taw3 | MJ_1538 | MJ_1510 | Yeast KTI12 Protein; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.504 |
| rgy | MJ_1511 | MJ_1512 | MJ_1511 | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.43; identified by sequence similarity; putative. | 0.454 |
| rgy | MJ_1559 | MJ_1512 | MJ_1559 | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family. | 0.481 |
| rgy | taw3 | MJ_1512 | MJ_1510 | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.499 |
| taw1 | taw2 | MJ_0257 | MJ_1557 | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | Met-10+ related protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). | 0.965 |
| taw1 | taw3 | MJ_0257 | MJ_1510 | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.931 |
| taw1 | trm5b | MJ_0257 | MJ_0883 | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | Conserved hypothetical protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs. | 0.863 |
| taw1 | vapC4 | MJ_0257 | MJ_1320 | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB4 (By similarity). Belongs to the PINc/VapC protein family. | 0.530 |
| taw2 | endA | MJ_1557 | MJ_1424 | Met-10+ related protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). | tRNA intron endonuclease (endA); Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.503 |
| taw2 | taw1 | MJ_1557 | MJ_0257 | Met-10+ related protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). | Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.965 |
| taw2 | taw3 | MJ_1557 | MJ_1510 | Met-10+ related protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | 0.993 |
| taw3 | MJ_0104 | MJ_1510 | MJ_0104 | Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. | DNA-binding protein, probably DNA helicase; Similar to GB:M64979 GB:L14754 GB:L24544 SP:P38935 PID:401776 percent identity: 34.98; identified by sequence similarity; putative; Belongs to the DNA2/NAM7 helicase family. | 0.729 |
