| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_0421 | MJ_1359 | MJ_0421 | MJ_1359 | Conserved hypothetical protein; Similar to GP:1786625 percent identity: 35.10; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GP:1653852 percent identity: 35.56; identified by sequence similarity; putative; Belongs to the UPF0273 family. | 0.468 |
| MJ_0421 | rgy | MJ_0421 | MJ_1512 | Conserved hypothetical protein; Similar to GP:1786625 percent identity: 35.10; identified by sequence similarity; putative. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.642 |
| MJ_1053 | MJ_1359 | MJ_1053 | MJ_1359 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1053. | Conserved hypothetical protein; Similar to GP:1653852 percent identity: 35.56; identified by sequence similarity; putative; Belongs to the UPF0273 family. | 0.483 |
| MJ_1053 | rgy | MJ_1053 | MJ_1512 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1053. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.640 |
| MJ_1130 | pcn | MJ_1130 | MJ_0247 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.447 |
| MJ_1130 | rgy | MJ_1130 | MJ_1512 | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.566 |
| MJ_1359 | MJ_0421 | MJ_1359 | MJ_0421 | Conserved hypothetical protein; Similar to GP:1653852 percent identity: 35.56; identified by sequence similarity; putative; Belongs to the UPF0273 family. | Conserved hypothetical protein; Similar to GP:1786625 percent identity: 35.10; identified by sequence similarity; putative. | 0.468 |
| MJ_1359 | MJ_1053 | MJ_1359 | MJ_1053 | Conserved hypothetical protein; Similar to GP:1653852 percent identity: 35.56; identified by sequence similarity; putative; Belongs to the UPF0273 family. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1053. | 0.483 |
| MJ_1359 | rgy | MJ_1359 | MJ_1512 | Conserved hypothetical protein; Similar to GP:1653852 percent identity: 35.56; identified by sequence similarity; putative; Belongs to the UPF0273 family. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.703 |
| MJ_1493 | rgy | MJ_1493 | MJ_1512 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1493. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.688 |
| fbp | rgy | MJ_0299 | MJ_1512 | Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.589 |
| hmgA | pcn | MJ_0705 | MJ_0247 | 3-hydroxy-3-methylglutaryl coenzyme A reductase; Converts HMG-CoA to mevalonate. | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.615 |
| hmgA | rgy | MJ_0705 | MJ_1512 | 3-hydroxy-3-methylglutaryl coenzyme A reductase; Converts HMG-CoA to mevalonate. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.646 |
| hmgA | rnhB | MJ_0705 | MJ_0135 | 3-hydroxy-3-methylglutaryl coenzyme A reductase; Converts HMG-CoA to mevalonate. | Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.697 |
| pcn | MJ_1130 | MJ_0247 | MJ_1130 | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...] | 0.447 |
| pcn | hmgA | MJ_0247 | MJ_0705 | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase; Converts HMG-CoA to mevalonate. | 0.615 |
| pcn | rgy | MJ_0247 | MJ_1512 | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | 0.750 |
| pcn | rnhB | MJ_0247 | MJ_0135 | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.973 |
| rgy | MJ_0421 | MJ_1512 | MJ_0421 | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Conserved hypothetical protein; Similar to GP:1786625 percent identity: 35.10; identified by sequence similarity; putative. | 0.642 |
| rgy | MJ_1053 | MJ_1512 | MJ_1053 | Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1053. | 0.640 |
