Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1521Na+/H+ antiporter; This is probably a Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (422 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.638
MJ_1226
Plasma membrane ATPase 1 (aha1); Similar to SP:P20649 percent identity: 44.42; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
   
 
 0.627
MJ_0091
Na+/Ca+ exchanger protein, putative; Similar to SP:P45394 PID:606134 GB:U00096 PID:1789587 percent identity: 31.58; identified by sequence similarity; putative.
 
 
 
 0.605
MJ_0104
DNA-binding protein, probably DNA helicase; Similar to GB:M64979 GB:L14754 GB:L24544 SP:P38935 PID:401776 percent identity: 34.98; identified by sequence similarity; putative; Belongs to the DNA2/NAM7 helicase family.
   
 
 0.590
MJ_0912
Conserved hypothetical protein; Similar to GP:1788638 percent identity: 31.17; identified by sequence similarity; putative.
   
 
 0.590
MJ_1520
Bacteriochlorophyll synthase 43 kDa subunit (chlP); Similar to SP:P26172 PID:46117 percent identity: 29.12; identified by sequence similarity; putative; Belongs to the geranylgeranyl reductase family. ChlP subfamily.
  
  
 0.582
cbiE
Cobalamin biosynthesis precorrin-6Y methylase (cbiE); Catalyzes the methylation of C-5 in cobalt-precorrin-7 to form cobalt-precorrin-8.
       0.493
MJ_0920
GTP-binding protein homologue (yphC); Similar to PID:1146219 SP:P50743 GB:AL009126 percent identity: 26.99; identified by sequence similarity; putative.
  
 0.466
crcB
Conserved hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.458
MJ_1275
NA(+)/H(+) antiporter (napA); This is probably a Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
   
 
 0.453
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (18%) [HD]