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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1526Conserved hypothetical protein; Similar to GB:M36534 PID:149753 PID:809716 percent identity: 41.30; identified by sequence similarity; putative; Belongs to the UPF0280 family. (244 aa)    
Predicted Functional Partners:
MJ_0100
Conserved hypothetical protein; Similar to PID:1652054 percent identity: 48.63; identified by sequence similarity; putative.
 
   
 0.843
MJ_0099
Ferredoxin II; Similar to SP:P00211 percent identity: 40.00; identified by sequence similarity; putative.
 
   
 0.831
MJ_1681
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 46.61; identified by sequence similarity; putative.
 
   
 0.765
MJ_1527
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 45.92; identified by sequence similarity; putative.
       0.762
bioB
Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
    0.720
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P).
       0.604
ogt
methylated-DNA-protein-cysteine methyltransferase, putative (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.455
asd
Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate. To a lesser extent, is able to use NAD instead of NADP. Belongs to the aspartate-semialdehyde dehydrogenase family.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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