Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1531Type I restriction-modification enzyme, S subunit, putative; Similar to GB:X17591 PID:40467 percent identity: 37.84; identified by sequence similarity; putative; To M.jannaschii MJ0130 and MJ1218. (425 aa)    
Predicted Functional Partners:
MJ_1220
Type I restriction-modification enzyme 1, M subunit; Similar to GB:L25415 PID:496158 percent identity: 32.85; identified by sequence similarity; putative.
 
 
 0.969
MJ_0132
Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.
 
 
 0.966
MJ_1214
Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.
 
  
 0.854
MJ_0124
Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.
 
  
 0.852
MJ_1530
Ribosomal protein S18 alanine acetyltransferase; Similar to GP:1707812 percent identity: 36.11; identified by sequence similarity; putative.
       0.773
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA1); Similar to SP:P10371 PID:41713 GB:U00096 PID:1736702 PID:1736711 percent identity: 32.64; identified by sequence similarity; putative.
       0.658
mjaIVMP
Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence GTNNAC, causes specific methylation on ? on both strands, and protects the DNA from cleavage by the MjaIV endonuclease.
 
  
 0.532
ogt
methylated-DNA-protein-cysteine methyltransferase, putative (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.467
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P).
     
 0.415
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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