STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1533Conserved hypothetical protein; Similar to GB:X04021 PID:44719 PID:44720 percent identity: 67.05; identified by sequence similarity; putative. (642 aa)    
Predicted Functional Partners:
flaK
Hypothetical protein; Cleaves the N-terminal leader peptide from preflagellins.
     
 0.739
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (hisIE); Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.685
MJ_1288
Type II secretion system protein; Similar to GP:1707774 percent identity: 29.44; identified by sequence similarity; putative; Belongs to the GSP E family.
 
   
 0.680
hisS
histidyl-tRNA synthetase (hisS); Similar to SP:P30053 percent identity: 35.44; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.672
flaJ
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 28.40; identified by sequence similarity; putative; To M.jannaschii MJ1286.
  
   
 0.666
MJ_0900
Type II secretion system protein; Identified by sequence similarity; putative; Belongs to the GSP E family.
 
   
 0.665
flaH
Flagella-related protein H, putative; Similar to GP:2104780 percent identity: 67.39; identified by sequence similarity; putative.
      
 0.618
MJ_1286
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 26.90; identified by sequence similarity; putative.
 
   
 0.584
cca
tRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
  
   
 0.565
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala) (By similarity). Also functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala), and maybe also from Gly-tRNA(Ala).
 
     0.536
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.