STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
merN5,N10-methylene-tetrahydromethanopterin reductase (mer); Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (331 aa)    
Predicted Functional Partners:
MJ_0725
Coenzyme F420-reducing hydrogenase, beta subunit; Similar to GB:J02914 SP:P19499 PID:149718 GB:AE000666 percent identity: 42.24; identified by sequence similarity; putative; Belongs to the FrhB family.
 
 
 0.964
frhB
Coenzyme F420-reducing hydrogenase, beta subunit (frhB); Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen. Belongs to the FrhB family.
 
 
 0.963
mtd
N5,N10-methylene-tetrahydromethanopterin dehydrogenase (mtd); Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
   
 
 0.958
MJ_1349
Coenzyme F420-reducing hydrogenase, beta subunit; Similar to GB:X61201 PID:809731 SP:Q00391 percent identity: 35.74; identified by sequence similarity; putative; Belongs to the FrhB family.
 
 
 0.957
frhG
Coenzyme F420-reducing hydrogenase, gamma subunit; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
   
 
 0.947
mtrA
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit A (mtrA); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
    
 0.947
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H (mtrH); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
 
  
 0.942
frhD
Coenzyme F420-reducing hydrogenase, delta subunit (frcD); Similar to GB:X61202 PID:44706 percent identity: 65.70; identified by sequence similarity; putative; Belongs to the peptidase A31 family.
  
 
 0.922
MJ_0253
Coenzyme F420-reducing hydrogenase, delta subunit (frcD); Similar to GB:X61201 PID:44702 percent identity: 45.45; identified by sequence similarity; putative; Belongs to the peptidase A31 family.
  
 
 0.922
MJ_0726
Coenzyme F420-reducing hydrogenase, gamma subunit; Similar to GB:X61201 PID:809730 SP:Q00393 percent identity: 43.53; identified by sequence similarity; putative; Belongs to the FrhG family.
   
 
 0.922
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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