STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1536Thioredoxin reductase (trxB); Similar to GB:U02197 GB:L43967 SP:P47348 PID:1045780 percent identity: 38.93; identified by sequence similarity; putative. (301 aa)    
Predicted Functional Partners:
trx
Thioredoxin (trx); Acts to maintain redox homeostasis; functions as a protein disulfide reductase.
  
 
 0.978
MJ_0736
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.934
MJ_0636
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative.
 
 
 0.855
MJ_0581
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase (By similarity). Has low thioredoxin activity in vitro (By similarity).
  
 
 0.810
MJ_1537
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1537.
       0.786
MJ_0263
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 34.57; identified by sequence similarity; putative.
  
  
 0.743
MJ_0940
Transformation sensitive protein; Similar to GB:M86752 SP:P31948 PID:184565 percent identity: 30.84; identified by sequence similarity; putative.
  
  
 0.743
MJ_0273
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0273.
       0.662
MJ_0774
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0774.
 
   
 0.657
MJ_1411
Glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent (gapN); Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP.
 
  
 0.635
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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