Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1552Conserved hypothetical protein; Similar to PID:1197355 percent identity: 48.44; identified by sequence similarity; putative. (141 aa)    
Predicted Functional Partners:
MJ_1549
3-keto-acyl-CoA thiolase; Similar to GP:2190267 percent identity: 31.48; identified by sequence similarity; putative.
 
 
 0.999
MJ_1546
Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 
 0.998
MJ_1545
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.42; identified by sequence similarity; putative.
  
    0.921
MJ_1551
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 43.86; identified by sequence similarity; putative.
       0.860
MJ_1553
Transcriptional regulatory protein, arsR family; Similar to SP:P37309 GB:X80057 PID:466638 PID:510825 GB:U00096 percent identity: 32.31; identified by sequence similarity; putative.
       0.705
MJ_0832
Anaerobic ribonucleoside-triphosphate reductase (nrdD); Similar to SP:P28903 GB:L06097 GB:U06195 GB:Z46865 PID:146970 percent identity: 28.17; identified by sequence similarity; putative.
       0.701
MJ_0240
Conserved hypothetical protein; Could catalyze the biosynthesis of cyclic AMP (cAMP) from ATP.
       0.685
MJ_0694
Conserved hypothetical protein; Similar to SP:Q12499 PID:1420682 PID:940841 percent identity: 43.15; identified by sequence similarity; putative.
       0.638
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
       0.638
hmgA
3-hydroxy-3-methylglutaryl coenzyme A reductase; Converts HMG-CoA to mevalonate.
       0.575
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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