STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
MJ_1562Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ1562. (388 aa)    
Predicted Functional Partners:
MJ_1563
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1563; Belongs to the GbsR family.
       0.948
MJ_1561
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1561.
  
  
 0.812
MJ_0917
Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP. Kinase can use ATP and other nucleoside triphosphates (UTP, TTP, CTP, GTP) as well as inorganic polyphosphate (poly(P)) as phosphoryl donors, however poly(P) is not considered to be the phys [...]
       0.624
MJ_1560
Multidrug-efflux transporter (bmr1); Similar to GB:L25604 SP:P33449 GB:M33768 PID:142606 PID:409287 percent identity: 28.57; identified by sequence similarity; putative.
       0.580
MJ_0687
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 40.25; identified by sequence similarity; putative.
  
  
 0.435
MJ_1623
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1623.
       0.422
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.418
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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