Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1568Conserved hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (173 aa)    
Predicted Functional Partners:
MJ_1566
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1566.
       0.956
MJ_1567
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1567.
       0.956
cca
tRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
 
   
 0.753
hel308
Putative SKI2-family helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks; Belongs to the helicase family. Hel308 subfamily.
  
  
 0.692
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation (By similarity).
       0.617
bioD
Dethiobiotin synthetase (bioD); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.595
eif6
Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex; Belongs to the eIF-6 family.
       0.575
rpl31e
LSU ribosomal protein L31E; Similar to SP:P04649 PID:1431090 PID:4390 PID:625117 PID:625117 percent identity: 42.25; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL31 family.
       0.575
rpl39e
LSU ribosomal protein L39E; Similar to SP:P13005 GB:X77509 PID:453438 percent identity: 52.94; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL39 family.
       0.575
MJ_1211
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1211.
       0.575
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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