Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1569Cobalamin biosynthesis protein (cbiM); May be involved in metal transport; Belongs to the CbiM family. (222 aa)    
Predicted Functional Partners:
MJ_1571
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 27.87; identified by sequence similarity; putative.
 
 0.999
MJ_1570
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1570.
  
 
 0.992
MJ_1572
Cobalt transport ATP-binding protein (cbiO); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.986
MJ_1089
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 42.68; identified by sequence similarity; putative.
 
 
 0.967
ecfA
Cobalt transport ATP-binding protein (cbiO); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.966
cbiN
Cobalt transport protein (cbiN); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
  
 
 0.934
cbiM
Cobalamin biosynthesis protein (cbiM); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
0.914
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA; Belongs to the NOP10 family.
       0.678
MJ_1210
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative.
       0.678
eif2a
Translation initiation factor aIF-2, subunit alpha (aif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
       0.677
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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