Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1599Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1599. (277 aa)    
Predicted Functional Partners:
MJ_1598
Conserved hypothetical protein; Similar to GP:1652098 percent identity: 35.67; identified by sequence similarity; putative; Belongs to the UPF0284 family.
       0.748
MJ_0804
Pyruvate formate-lyase activating enzyme (act); Similar to GB:L42023 SP:P43751 PID:1003258 PID:1222095 PID:1204435 percent identity: 29.66; identified by sequence similarity; putative.
 
   
 0.730
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.643
MJ_0906
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0906.
 
 
 0.578
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.565
MJ_1601
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 31.48; identified by sequence similarity; putative.
       0.565
pfkC
Hypothetical protein; Catalyzes the phosphorylation of fructose 6-phosphate and D- glucose to fructose 1,6-bisphosphate and D-glucose 6-phosphate, respectively, using ADP as the phosphate donor; Belongs to the carbohydrate kinase PfkC family.
  
     0.563
hom
Homoserine dehydrogenase (hom); Similar to SP:P19582 GB:M23217 PID:558494 PID:809663 GB:AL009126 percent identity: 40.32; identified by sequence similarity; putative; Belongs to the homoserine dehydrogenase family.
     
 0.543
MJ_0500
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 25.14; identified by sequence similarity; putative.
  
    0.519
MJ_1650
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 31.03; identified by sequence similarity; putative.
  
    0.510
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (8%) [HD]