STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase; Catalyzes the isomerization of glucose-6-P to fructose-6-P. (401 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P).
  
 0.996
pfkC
Hypothetical protein; Catalyzes the phosphorylation of fructose 6-phosphate and D- glucose to fructose 1,6-bisphosphate and D-glucose 6-phosphate, respectively, using ADP as the phosphate donor; Belongs to the carbohydrate kinase PfkC family.
    
 0.993
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.989
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.988
pgk
Phosphoglycerate kinase (pgk); Similar to GB:M55529 SP:P20971 PID:149808 percent identity: 56.76; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
  
 
 0.987
gap
Glyceraldehyde 3-phosphate dehydrogenase; Similar to SP:P10618 PID:149792 percent identity: 60.00; identified by sequence similarity; putative.
  
 
 0.986
phi
Conserved hypothetical protein; Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate; Belongs to the SIS family. PHI subfamily.
    
 0.981
glgA
Glycogen synthase (glgA); Synthesizes alpha-1,4-glucan chains using ADP-glucose.
  
  
 0.977
MJ_0108
Pyruvate kinase; Similar to GB:D13095 SP:Q02499 GB:X57859 PID:285623 percent identity: 38.82; identified by sequence similarity; putative.
 
 
 0.975
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) (glmS); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.960
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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