STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apgM1Phosphonopyruvate decarboxylase (bcpC); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (411 aa)    
Predicted Functional Partners:
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.924
MJ_1611
Alpha-amylase (amyA); Similar to GB:L22346 SP:P49067 PID:347940 percent identity: 27.10; identified by sequence similarity; putative.
       0.923
apgM2
BcpC phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
0.920
pgk
Phosphoglycerate kinase (pgk); Similar to GB:M55529 SP:P20971 PID:149808 percent identity: 56.76; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
    
 0.919
serA
Phosphoglycerate dehydrogenase (serA); Similar to GB:L09228 SP:P35136 PID:1146196 PID:410116 GB:AL009126 percent identity: 42.02; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.910
MJ_1185
Putative aldehyde ferredoxin oxidoreductase (aor); Similar to PID:736274 percent identity: 26.51; identified by sequence similarity; putative; Belongs to the AOR/FOR family.
    
  0.902
pgi
Glucose-6-phosphate isomerase; Catalyzes the isomerization of glucose-6-P to fructose-6-P.
  
 
 0.871
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.833
aroA
Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. Can also catalyze the cleavage of fructose-1,6- bisphosphate (FBP) to glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).
     
 0.827
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
     
 0.820
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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