STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1614Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 30.52; identified by sequence similarity; putative; To M.jannaschii MJ1311. (251 aa)    
Predicted Functional Partners:
MJ_1613
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 35.42; identified by sequence similarity; putative.
 
     0.957
MJ_1615
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1615.
       0.778
MJ_1188
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 33.21; identified by sequence similarity; putative.
 
     0.635
MJ_0406
Ribokinase (rbsK); Catalyzes the phosphorylation of a wide range of nucleosides to yield nucleoside monophosphates. Shows the highest activity for inosine, guanosine and cytidine, but very poor kinase activity with adenosine, thymidine, uridine and xanthosine. ATP is the best phosphate donor, but can also use ITP and GTP. Shows extremely low activity with fructose-6-phosphate; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.555
MJ_1336
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1336.
  
  
 0.555
guaB
Inosine-5'-monophosphate dehydrogenase, (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.489
MJ_1617
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1617.
       0.426
MJ_1411
Glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent (gapN); Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP.
  
  
 0.425
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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