Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1632Coenzyme PQQ synthesis protein (pqqE); Similar to SP:P27507 PID:809708 percent identity: 27.45; identified by sequence similarity; putative. (255 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.856
MJ_1631
Glycogen phosphorylase (glgP); Similar to GB:Z25795 SP:P39123 PID:397492 PID:2293140 GB:AL009126 percent identity: 27.95; identified by sequence similarity; putative; Belongs to the glycogen phosphorylase family.
       0.773
MJ_0832
Anaerobic ribonucleoside-triphosphate reductase (nrdD); Similar to SP:P28903 GB:L06097 GB:U06195 GB:Z46865 PID:146970 percent identity: 28.17; identified by sequence similarity; putative.
 
   
 0.626
MJ_0717
Molybdopterin converting factor, subunit 2 (moaE); Similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003 percent identity: 31.52; identified by sequence similarity; putative; To Synechocystis PCC 6803 slr0903.
  
  
 0.556
thyA
Thymidylate synthase (thyA); May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
  
  
 0.526
fdhD
Formate dehydrogenase (fdhD); Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family.
  
  
 0.524
MJ_0804
Pyruvate formate-lyase activating enzyme (act); Similar to GB:L42023 SP:P43751 PID:1003258 PID:1222095 PID:1204435 percent identity: 29.66; identified by sequence similarity; putative.
 
  
 0.504
moaB
Molybdenum cofactor biosynthesis protein (moaB); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor.
  
  
 0.478
cobQ
Cobyric acid synthase (cbiP); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily.
     
 0.446
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.