Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1633Conserved hypothetical protein; Similar to GP:1652055 percent identity: 37.46; identified by sequence similarity; putative. (478 aa)    
Predicted Functional Partners:
mptE
Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
       0.717
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation (By similarity).
   
 0.645
MJ_1601
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 31.48; identified by sequence similarity; putative.
 
     0.533
MJ_0274
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.09; identified by sequence similarity; putative.
 
     0.510
MJ_1134
Conserved hypothetical protein; Similar to GB:L09228 SP:P35154 PID:410131 GB:AL009126 percent identity: 21.63; identified by sequence similarity; putative.
 
    0.505
infB
Translation initiation factor aIF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
  
  
 0.494
MJ_0661
Conserved hypothetical protein; Similar to GP:1001294 percent identity: 32.39; identified by sequence similarity; putative; To H.pylori HP0274.
 
    0.480
MJ_0021
Conserved hypothetical protein; Similar to GP:1707810 percent identity: 43.12; identified by sequence similarity; putative.
  
     0.461
engB
Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
 
     0.454
MJ_1127
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 46.18; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily.
  
     0.412
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.