STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1662Methyl coenzyme M reductase system, component A2-like; Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 37.07; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (555 aa)    
Predicted Functional Partners:
MJ_1089
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 42.68; identified by sequence similarity; putative.
  
 
 0.892
MJ_1571
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 27.87; identified by sequence similarity; putative.
  
 
 0.892
MJ_1572
Cobalt transport ATP-binding protein (cbiO); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
0.798
ecfA
Cobalt transport ATP-binding protein (cbiO); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
0.797
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H (mtrH); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
  
  0.768
vhuA
Methylviologen-reducing hydrogenase, alpha chain (vhuA); Similar to GB:X61204 PID:44799 PID:1747408 percent identity: 77.03; identified by sequence similarity; putative.
    
 0.673
MJ_0006
Formate dehydrogenase, alpha subunit; Similar to GB:J02581 SP:P06131 PID:149708 percent identity: 41.56; identified by sequence similarity; putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
  0.672
hdrC1
Heterodisulfide reductase, subunit C (hdrC); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.
     
 0.671
hdrC2
Heterodisulfide reductase, subunit C2 (hdrC2); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.
     
 0.671
vhuG
Methylviologen-reducing hydrogenase, gamma chain (vhuG); Similar to GB:X61204 PID:44798 PID:1747407 percent identity: 71.13; identified by sequence similarity; putative.
    
 0.671
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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