djlA protein (Methylococcus capsulatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

djlA

DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. (276 aa)

Predicted Functional Partners:

dnaK

0.842

MCA0239

0.780

MCA0248

0.780

MCA0988

0.780

MCA0599

0.758

MCA0600

0.708

MCA2124

0.666

purC

0.639

gmd

0.618

MCA1168

0.618

Your Current Organism:

Methylococcus capsulatus

NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCA0239	djlA	MCA0239	MCA0020	Putative nitrogen fixation protein nifQ; Identified by similarity to SP:P11068; match to protein family HMM PF04891.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.780
MCA0239	dnaK	MCA0239	MCA1856	Putative nitrogen fixation protein nifQ; Identified by similarity to SP:P11068; match to protein family HMM PF04891.	dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.502
MCA0248	djlA	MCA0248	MCA0020	NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.780
MCA0248	dnaK	MCA0248	MCA1856	NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.555
MCA0599	MCA0600	MCA0599	MCA0600	Identified by similarity to GP:4545244; match to protein family HMM PF00483.	Conserved hypothetical protein; Identified by similarity to GP:4545243.	0.999
MCA0599	djlA	MCA0599	MCA0020	Identified by similarity to GP:4545244; match to protein family HMM PF00483.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.758
MCA0600	MCA0599	MCA0600	MCA0599	Conserved hypothetical protein; Identified by similarity to GP:4545243.	Identified by similarity to GP:4545244; match to protein family HMM PF00483.	0.999
MCA0600	djlA	MCA0600	MCA0020	Conserved hypothetical protein; Identified by similarity to GP:4545243.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.708
MCA0988	djlA	MCA0988	MCA0020	NifU family protein; Identified by similarity to SP:P77310; match to protein family HMM PF01592; match to protein family HMM TIGR01994.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.780
MCA0988	dnaK	MCA0988	MCA1856	NifU family protein; Identified by similarity to SP:P77310; match to protein family HMM PF01592; match to protein family HMM TIGR01994.	dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.555
MCA1168	MCA2124	MCA1168	MCA2124	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534.	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534.	0.642
MCA1168	djlA	MCA1168	MCA0020	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.618
MCA1168	dnaK	MCA1168	MCA1856	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534.	dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.625
MCA1168	gmd	MCA1168	MCA1146	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534.	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.	0.936
MCA2124	MCA1168	MCA2124	MCA1168	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534.	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534.	0.642
MCA2124	djlA	MCA2124	MCA0020	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534.	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	0.666
MCA2124	dnaK	MCA2124	MCA1856	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534.	dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.625
MCA2124	gmd	MCA2124	MCA1146	Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534.	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.	0.629
djlA	MCA0239	MCA0020	MCA0239	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	Putative nitrogen fixation protein nifQ; Identified by similarity to SP:P11068; match to protein family HMM PF04891.	0.780
djlA	MCA0248	MCA0020	MCA0248	DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.	NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.780

page 1 of 2

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About