Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCA0042Antioxidant, AhpC/Tsa family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (168 aa)    
Predicted Functional Partners:
bsaA
Glutathione peroxidase; Identified by similarity to SP:P52035; match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
   
 0.930
MCA1023
Identified by match to protein family HMM PF00578.
   
 0.918
MCA1002
Glutathione S-transferase domain protein; Identified by match to protein family HMM PF02798.
  
 
  0.915
gshB
Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family.
     
 0.901
gst
Glutathione S-transferase; Identified by similarity to SP:P39100; match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.
   
 
  0.900
gstB
Glutathione S-transferase; Identified by similarity to SP:P39100; match to protein family HMM PF02798.
   
 
  0.900
ggt
Gamma-glutamyltranspeptidase; Identified by similarity to SP:P18956; match to protein family HMM PF01019; match to protein family HMM TIGR00066.
     
  0.900
MCA0686
Conserved hypothetical protein; Identified by similarity to SP:P58039; match to protein family HMM PF03692.
   
   0.732
rpiB
Ribose 5-phosphate isomerase B; Identified by similarity to SP:P37351; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120.
       0.636
dsbE-1
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
   
 0.510
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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