Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA0047Carbohydrate kinase, PfkB family; Identified by match to protein family HMM PF00294. (310 aa)    
Predicted Functional Partners:
MCA0046
MazG family protein; Identified by similarity to OMNI:CC1747; match to protein family HMM PF03819; match to protein family HMM TIGR00444.
    
  0.979
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.932
purB
Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.926
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.912
MCA0973
Conserved hypothetical protein TIGR00726; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
  0.911
MCA0448
5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family.
    
 0.904
MCA3091
Decarboxylase family protein; Identified by similarity to OMNI:VC0899; match to protein family HMM PF03641.
    
  0.902
cpdA
Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
  0.901
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
MCA1322
5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189.
     
  0.900
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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