| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0105 | mrcA | MCA0105 | MCA0324 | D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. | Penicillin-binding protein 1A; Identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074. | 0.911 |
| MCA0105 | mrdA | MCA0105 | MCA0103 | D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.905 |
| MCA0105 | mreB | MCA0105 | MCA0100 | D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. | Rod shape-determining protein MreB; Identified by similarity to SP:P13519; match to protein family HMM PF06723; match to protein family HMM TIGR00904. | 0.577 |
| MCA0105 | mreC | MCA0105 | MCA0101 | D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.613 |
| MCA0105 | mreD | MCA0105 | MCA0102 | D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.469 |
| MCA0105 | rodA | MCA0105 | MCA0104 | D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.643 |
| MCA1672 | ftsI | MCA1672 | MCA2434 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.822 |
| MCA1672 | ftsQ | MCA1672 | MCA2425 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Putative cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.562 |
| MCA1672 | ftsW | MCA1672 | MCA2430 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.645 |
| MCA1672 | mrcA | MCA1672 | MCA0324 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein 1A; Identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074. | 0.952 |
| MCA1672 | mrdA | MCA1672 | MCA0103 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.751 |
| MCA1672 | mreB | MCA1672 | MCA0100 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Rod shape-determining protein MreB; Identified by similarity to SP:P13519; match to protein family HMM PF06723; match to protein family HMM TIGR00904. | 0.819 |
| MCA1672 | mreC | MCA1672 | MCA0101 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.608 |
| MCA1672 | mreD | MCA1672 | MCA0102 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.521 |
| MCA1672 | rodA | MCA1672 | MCA0104 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.683 |
| ftsI | MCA1672 | MCA2434 | MCA1672 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.822 |
| ftsI | ftsQ | MCA2434 | MCA2425 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Putative cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.950 |
| ftsI | ftsW | MCA2434 | MCA2430 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.990 |
| ftsI | mrcA | MCA2434 | MCA0324 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein 1A; Identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074. | 0.768 |
| ftsI | mrdA | MCA2434 | MCA0103 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.941 |
STRING v12.5 is now available!
