Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mgtEMagnesium transporter; Acts as a magnesium transporter. (481 aa)    
Predicted Functional Partners:
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
       0.793
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
       0.773
MCA0106
Putative D-amino acid aminotransferase; Identified by similarity to SP:P54692; match to protein family HMM PF01063.
     
 0.538
MCA0111
Conserved hypothetical protein; Identified by similarity to OMNI:MT0787.
       0.535
MCA0105
D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family.
     
 0.532
MCA0107
Conserved hypothetical protein; Identified by similarity to GP:17427335; match to protein family HMM PF04359; Belongs to the UPF0250 family.
       0.532
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.491
MCA1872
C4-dicarboxylate transporter; Identified by similarity to SP:P37312; match to protein family HMM PF00375; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
     
 0.484
MCA1456
Magnesium and cobalt efflux protein CorC; Identified by similarity to SP:Q9R874; match to protein family HMM PF00571; match to protein family HMM PF03471.
      
 0.440
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
       0.432
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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