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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hoxWHoxW protein; Identified by similarity to GP:1313919. (180 aa)    
Predicted Functional Partners:
MCA0114
NAD-reducing hydrogenase, beta subunit; Identified by similarity to SP:P22320; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.962
MCA2726
NAD-reducing hydrogenase, delta subunit; Identified by similarity to SP:P22319; match to protein family HMM PF01058.
 
  
 0.846
MCA2725
NAD-reducing hydrogenase, gamma subunit; Identified by similarity to SP:P22318; match to protein family HMM PF00111.
 
   
 0.806
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
      
 0.750
MCA2724
NAD-reducing hydrogenase, alpha subunit; Identified by similarity to SP:P22317; match to protein family HMM PF01257; match to protein family HMM PF01512.
 
   
 0.731
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
      
 0.634
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
      
 0.616
hemN
Oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055; match to protein family HMM PF06969; match to protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.584
MCA1138
Hydrogenase subunit; Identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346.
  
  
 0.564
MCA0116
Conserved hypothetical protein; Identified by similarity to GP:19914581; match to protein family HMM PF06803.
       0.424
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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