Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (278 aa)    
Predicted Functional Partners:
apaG
apaG protein; Identified by similarity to SP:Q56017; match to protein family HMM PF04379.
  
  
 0.840
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
   
 0.839
MCA2643
Conserved hypothetical protein; Identified by similarity to GP:17427847.
   
 0.760
MCA2041
Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
  
   0.731
MCA1130
Identified by match to protein family HMM PF00753; match to protein family HMM PF07521.
    
  0.709
MCA0523
Putative peptidyl-prolyl cis-trans isomerase, FKBP-type; Identified by similarity to SP:P45523; match to protein family HMM PF00254.
    
 
 0.695
ftsB
Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.643
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.
  
     0.640
sspB
Identified by similarity to SP:P25663; match to protein family HMM PF04386.
  
     0.623
sspA
Identified by match to protein family HMM PF00043; match to protein family HMM PF02798.
  
 
 
 0.579
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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