Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA0161Putative hydrogenase expression/formation protein; Identified by similarity to SP:P19932; match to protein family HMM PF04809. (278 aa)    
Predicted Functional Partners:
MCA0163
Nickel-iron hydrogenase, small subunit; Identified by similarity to SP:Q43953; match to protein family HMM PF01292; match to protein family HMM TIGR02125.
 
  
 0.983
MCA0162
Hydrogenase expression/formation protein; Identified by similarity to SP:Q03004; match to protein family HMM PF01750; match to protein family HMM TIGR00072; match to protein family HMM TIGR00140; match to protein family HMM TIGR00141.
 
  
 0.960
MCA0166
Nickel-iron hydrogenase, small subunit; Identified by similarity to SP:P21950; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409.
 
 
 0.951
MCA0165
Nickel-iron hydrogenase, large subunit; Identified by similarity to SP:P18636; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.945
MCA0164
Nickel-iron hydrogenase, accessory protein; Identified by similarity to GP:19421553; match to protein family HMM PF04955.
 
     0.718
MCA2116
Leucine rich repeat domain protein; Identified by match to protein family HMM PF01816.
  
     0.645
MCA0769
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176.
     
 0.592
MCA0208
Leucine rich repeat domain protein; Identified by match to protein family HMM PF01816.
  
     0.591
MCA0160
Hypothetical protein; Identified by Glimmer2; putative.
       0.568
MCA0232
Ferredoxin, 2Fe-2S; Identified by similarity to SP:P37097; match to protein family HMM PF00111.
  
    0.429
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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