STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0165Nickel-iron hydrogenase, large subunit; Identified by similarity to SP:P18636; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)    
Predicted Functional Partners:
MCA0166
Nickel-iron hydrogenase, small subunit; Identified by similarity to SP:P21950; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409.
 0.999
MCA0163
Nickel-iron hydrogenase, small subunit; Identified by similarity to SP:Q43953; match to protein family HMM PF01292; match to protein family HMM TIGR02125.
 
 
 0.997
MCA0162
Hydrogenase expression/formation protein; Identified by similarity to SP:Q03004; match to protein family HMM PF01750; match to protein family HMM TIGR00072; match to protein family HMM TIGR00140; match to protein family HMM TIGR00141.
 
 
 0.963
MCA0161
Putative hydrogenase expression/formation protein; Identified by similarity to SP:P19932; match to protein family HMM PF04809.
 
  
 0.945
MCA0769
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176.
   
  
 0.897
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.888
MCA2726
NAD-reducing hydrogenase, delta subunit; Identified by similarity to SP:P22319; match to protein family HMM PF01058.
  
 
 0.879
hypD
Hydrogenase expression/formation protein HypD; Identified by match to protein family HMM PF01924; Belongs to the HypD family.
 
 
 0.753
hypE
Hydrogenase expression/formation protein HypE; Identified by similarity to SP:P40595; match to protein family HMM PF02769; match to protein family HMM TIGR02124.
 
   
 0.732
hypB
Hydrogenase accessory protein HypB; Identified by similarity to SP:P24190; match to protein family HMM PF02492; match to protein family HMM TIGR00073.
 
   
 0.730
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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