Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA0196Conserved hypothetical protein; Identified by similarity to GP:18893692; match to protein family HMM PF01951. (143 aa)    
Predicted Functional Partners:
rtcB
Conserved hypothetical protein; Identified by similarity to GP:18893765; match to protein family HMM PF01139; Belongs to the RtcB family.
 
 0.995
MCA2379
Conserved hypothetical protein; Identified by similarity to GP:9950959.
   
    0.862
MCA0197
Conserved hypothetical protein; Identified by similarity to OMNI:NTL02SS0707; match to protein family HMM PF01864.
     
 0.816
cca
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
 
      0.781
MCA0194
Hypothetical protein; Identified by Glimmer2; putative.
       0.746
MCA0791
Putative transporter; Identified by similarity to OMNI:AF2308.
  
   
 0.699
MCA1346
Sodium/bile acid symporter family protein; Identified by match to protein family HMM PF01758.
      
 0.618
MCA2319
Putative formylmethanofurane dehydrogenase, subunit; Identified by similarity to GP:13559971; match to protein family HMM PF07969.
      
 0.618
MCA2732
Conserved hypothetical protein; Identified by similarity to GP:19915032.
      
 0.618
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007.
      
 0.618
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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